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The environment to traverse ( A ) and the simulation pipeline ( B ). The environment was generated as a linear combination of scaled and translated Gaussian surfaces, as described in Methods and Materials. The simulation procedure entailed refining the path predictions by each algorithm separately using the landscape-dependent cost function. Abbreviations: GA—genetic Algorithm; PSO—Particle Swarm Optimization; SQP— Sequential Quadratic Programming; a.u.—arbitrary units.

Journal: bioRxiv

Article Title: Evaluating Evolutionary and Gradient-Based Algorithms for Optimal Pathfinding

doi: 10.1101/2025.03.16.643541

Figure Lengend Snippet: The environment to traverse ( A ) and the simulation pipeline ( B ). The environment was generated as a linear combination of scaled and translated Gaussian surfaces, as described in Methods and Materials. The simulation procedure entailed refining the path predictions by each algorithm separately using the landscape-dependent cost function. Abbreviations: GA—genetic Algorithm; PSO—Particle Swarm Optimization; SQP— Sequential Quadratic Programming; a.u.—arbitrary units.

Article Snippet: The third algorithm used in our study was a quasi-Newton method—the Sequential Quadratic Programming (SQP) procedure (“ fmincon ” function in the MATLAB’s Optimization Toolbox)—described in detail in ( ).

Techniques: Generated, Refining

Representative paths calculated by the three evaluated algorithms: ( A ) Genetic Algorithm (GA), ( B ) Particle Swarm Optimization (PSO), and ( C ) Sequential Quadratic Programming (SQP), each illustrating the distinct pathfinding solutions. Abbreviations are the same as in .

Journal: bioRxiv

Article Title: Evaluating Evolutionary and Gradient-Based Algorithms for Optimal Pathfinding

doi: 10.1101/2025.03.16.643541

Figure Lengend Snippet: Representative paths calculated by the three evaluated algorithms: ( A ) Genetic Algorithm (GA), ( B ) Particle Swarm Optimization (PSO), and ( C ) Sequential Quadratic Programming (SQP), each illustrating the distinct pathfinding solutions. Abbreviations are the same as in .

Article Snippet: The third algorithm used in our study was a quasi-Newton method—the Sequential Quadratic Programming (SQP) procedure (“ fmincon ” function in the MATLAB’s Optimization Toolbox)—described in detail in ( ).

Techniques: